|
Référence |
traitement |
n pts |
RO (%) |
SM (mo) |
survie à 2 ans |
p |
|
Mattson, 1988 |
1. CPA-ADR-CDDP(2x) puis RT (55Gy) |
76 |
49 |
ND |
ND |
S |
|
2. RT (55Gy) |
78 |
44 |
ND |
ND |
||
|
Dillman, 1990 |
1. CDDP-VBL(2x) puis RT (60Gy) |
78 |
46 |
13,8 |
26% |
S |
|
2. RT (60Gy) |
77 |
35 |
9,7 |
13% |
||
|
Morton, 1991 |
1. MTX-ADR-CPA-CCNU(2x) puis RT (60 Gy) |
56 |
55 |
10 |
21% |
NS |
|
2. RT (60 Gy) |
58 |
64 |
10 |
16% |
||
|
Le Chevalier, 1991 |
1. VDS-CPA-CDDP-CCNU(3x) puis RT (65 Gy) |
176 |
31 |
12 |
21% |
S |
|
2. RT (65 Gy) |
177 |
35 |
10 |
14% |
||
|
Gregor, 1993 |
1. CDDP-VDS(2x) puis RT (50 Gy) |
39 |
62 |
12,1 |
ND |
NS |
|
2. RT (50 Gy) |
39 |
42 |
12,4 |
ND |
||
|
Crino, 1993 |
1. CDDP-VP16(3x) puis RT (56 Gy) |
29 |
53 |
12,1 |
28% |
NS |
|
2. RT (56 Gy) |
32 |
32 |
8.4 |
14% |
||
|
Wolf, 1997 |
1. Ifo-VDS (2x) puis RT (50 Gy) |
37 |
57 |
13,7 |
24 % |
S |
|
2. RT (50 Gy) |
41 |
41 |
9 |
12 % |
||
|
Sause, 1995 |
1. CDDP-VBL (2x) puis RT (60 Gy) |
164 |
ND |
13,8 |
ND |
S |
|
2. RT (60 Gy) |
163 |
ND |
11,4 |
ND |
||
|
3. bifractionated RT (69.6 Gy) |
163 |
ND |
12,3 |
ND |
||
|
Planting, 1996 |
1. CDDP-VDS (2x) puis RT (55Gy) |
37 |
41 |
12,0 |
ND |
NS |
|
2. RT (55 Gy) |
33 |
55 |
12,0 |
ND |
||
|
Brodin, 1996 |
1. CDDP-VP16 (2x) puis RT (56 Gy) |
163 |
26 |
11 |
21% |
NS |
|
2. RT (56 Gy) |
164 |
25 |
10,5 |
17% |
||
|
Cullen, 1999 |
1. MMC-Ifo-CDDP puis RT |
223 |
54 |
12 |
ND |
NS |
|
2. RT |
223 |
10 |
ND |
|||
|
Mattson, 2003 |
1. Docetaxel (x3) puis RT |
134 |
28 |
14,8 |
ND |
NS |
|
2. RT |
140 |
12,6 |
ND |