|
CANCERS BRONCHIQUES A PETITES CELLULES
TRAITEMENTS BIOLOGIQUES: INHIBITEURS DES MÉTALLOPROTÉASES
|
|
Référence |
chimiothérapie |
inhibiteur |
modalité |
stade |
nb pts |
SM CT |
SM CT + inh |
p |
Shepherd,
2002 |
Tout type |
marimastat |
entretien |
tous |
532 |
9,3 m |
9,7 m |
NS |
Références
(1) Shepherd FA, Giaccone G, Seymour L, Debruyne C, Bezjak A, Hirsh V et al. Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the European Organization for Research and Treatment of Cancer. J Clin Oncol 2002; 20(22):4434-4439.
|