|
CANCERS BRONCHIQUES NON A PETITES CELLULES : CHIMIOTHERAPIE NEOADJUVANTE
META-ANALYSES ET REVUES SYSTEMATIQUES
|
|
Référence
|
Méthodologie
|
Critère de jugement
|
Nombre d'essais
|
Nombre de patients
|
Résultat
|
Sculier,
2001 (1)
|
MARSL
|
Survie globale
|
4
|
173
|
S
HR
= 0,51 (IC 95% 0,34 - 0,76)
|
Berghmans,
2005 (2)
|
MARSL
|
Survie globale
|
6
|
590
|
S
HR
= 0,69 (IC 95% 0,57 – 0,84)
|
Burdett,
2005 (3)
|
MAI
|
|
12
|
988
|
S
HR
= 0,82 (IC 95% 0,69 – 0,97)
|
Nakamura,
2006 (4)
|
MAI
|
Survie à 5 ans
|
5
|
564
|
NS
HR
= 0,85 (IC 95% 0,70 - 1,04)
|
Lim,
2009 (5)
|
MARSL
|
Survie globale
|
10
|
|
S
HR
= 0,81 (IC 95% 0,68 – 0,97)
|
Song,
2010 (6)
|
MAI
|
Survie globale
|
13
|
3224
|
S
HR
= 0,84 (IC 95% 0,77 – 0,92)
|
Références
(1) Sculier JP, Berghmans T, Paesmans M, Branle F, Lemaitre F, Mascaux C, et al. La place de la chimiothérapie dans le traitement des cancers bronchiques non à petites cellules non métastatiques. [The role of chemotherapy in the treatment of non-metastatic, non-small cell bronchial cancers]. Rev Med Brux 2001 Dec;22(6):477-87.
(2) Berghmans T, Paesmans M, Meert AP, Mascaux C, Lothaire P, Lafitte JJ, et al. Survival improvement in resectable non-small cell lung cancer with (neo)adjuvant chemotherapy: results of a meta-analysis of the literature. Lung Cancer 2005;49:13-23.
(3) Burdett S SLRL. A systematic review and meta-analysis of the literature: chemotherapy and surgery versus surgery alone in non-small cell lung cancer. J Thorac Oncol 2006;1:611-21.
(4) Nakamura H, Kawasaki N, Taguchi M, Kabasawa K. Role of preoperative chemotherapy for non-small-cell lung cancer: a meta-analysis. Lung Cancer 2006 Dec;54(3):325-9.
(5) Lim E, Harris G, Patel A, Adachi I, Edmonds L, Song F. Preoperative versus postoperative chemotherapy in patients with resectable non-small cell lung cancer: systematic review and indirect comparison meta-analysis of randomized trials. J Thorac Oncol 2009 Nov;4(11):1380-8.
(6) Song WA, Zhou NK, Wang W, Chu XY, Liang CY, Tian XD, et al. Survival benefit of neoadjuvant chemotherapy in non-small cell lung cancer: an updated meta-analysis of 13 randomized control trials. J Thorac Oncol 2010 Apr;5(4):510-6.
|