CANCERS BRONCHIQUES NON A PETITES CELLULES AU STADE AVANCE |
|
|
référence |
chimiothérapie |
n |
(stIV) |
% RO |
p |
SM |
p |
|
Williamson, 2005 |
I. Paclitaxel (225) + Carboplatine (AUC 6) |
186 |
87 % |
35 |
NS |
9 m |
NS |
|
II. Idem + tirapazamine (260 mg/m²) |
181 |
84 % |
26 |
9 m |
Références
(1) Williamson SK, Crowley JJ, Lara PN, Jr., McCoy J, Lau DH, Tucker RW et al. Phase III Trial of Paclitaxel Plus Carboplatin With or Without Tirapazamine in Advanced Non-Small-Cell Lung Cancer: Southwest Oncology Group Trial S0003. J Clin Oncol 2005; 23(36):9097-9104.